Optimum Design of Remote Delivery Capsule’s Driving Mechanism Based on Electromagnetic-Permanent Magnet

doi:10.16182/j.issn1004731x.joss.201802046

Abstract

Abstract: To achieve fast, reliable and controllable drug delivery in the gastrointestinal lesions, a suitable delivery driving mechanism was studied. The structure of the driving mechanism was designedto overcome the magnetic force decaying rapidly with distance, whichcan satisfy the demands of the drug delivery for the large dose and long driving stroke.By combining the orthogonal test theory and the finite element simulation, the magnetic driving forcehas been calculatedforthe parameters of the electromagnetic coil and permanent magnet in different combinations of the values. The structure parameters of the electromagnetic coil and the permanent magnethave been optimizedto achieve the maximum magnetic driving force within the limited space.Themagnetic field distribution of the magnetic driving mechanismis simulatedby the optimized parameters. The simulation results show thatthe optimized magnetic driving force can satisfy the requirement of the medicine delivery, which provides a theoretical basis for developing the magnetic driving mechanism.

Key words: site-specific drug delivery, drug release driver, repeatedly release, orthogonal test, finite element simulation, magnetic field distribution

CLC Number:

Lu Zhengping, GuoXudong, Xu Tangcheng, Qin Ruihua. Optimum Design of Remote Delivery Capsule’s Driving Mechanism Based on Electromagnetic-Permanent Magnet[J]. Journal of System Simulation, 2018, 30(2): 747-752.

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