电磁-永磁式遥控施药胶囊驱动装置优化设计

doi:10.16182/j.issn1004731x.joss.201802046

系统仿真学报 ›› 2018, Vol. 30 ›› Issue (2): 747-752.doi: 10.16182/j.issn1004731x.joss.201802046

电磁-永磁式遥控施药胶囊驱动装置优化设计

鲁正平, 郭旭东, 许堂成, 秦锐华

上海理工大学医疗器械与食品学院,上海 200093

收稿日期:2016-01-13 出版日期:2018-02-08 发布日期:2019-01-02
作者简介:鲁正平(1990-),男,河南郑州,硕士生,研究方向为精密工程与智能微系统;郭旭东(1980-),女,湖南益阳,博士,副教授,研究方向为精密工程与智能微系统。
基金资助:
上海市自然科学基金 (15ZR1428200)

Optimum Design of Remote Delivery Capsule’s Driving Mechanism Based on Electromagnetic-Permanent Magnet

Lu Zhengping, GuoXudong, Xu Tangcheng, Qin Ruihua

School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China

Received:2016-01-13 Online:2018-02-08 Published:2019-01-02

摘要/Abstract

摘要： 为对胃肠道病灶处实现快速、可靠、可控的药物输送,研究了电磁-永磁式施药驱动装置。为克服磁力随距离迅速衰减,设计了驱动装置的结构,使其满足驱动行程大的药物释放需求;并结合正交试验理论和有限元仿真计算不同参数的磁场驱动力,优化电磁线圈和永磁体的结构参数,以实现有限空间内的最优驱动力。采用优化后的参数对磁力驱动装置中的磁场分布进行了仿真。仿真验证表明：优化后的驱动装置能满足施药所需的驱动力。为磁力驱动装置的实现提供了理论依据。

关键词: 定点药物释放, 施药驱动, 多次释放, 正交试验, 有限元仿真, 磁场分布

Abstract: To achieve fast, reliable and controllable drug delivery in the gastrointestinal lesions, a suitable delivery driving mechanism was studied. The structure of the driving mechanism was designedto overcome the magnetic force decaying rapidly with distance, whichcan satisfy the demands of the drug delivery for the large dose and long driving stroke.By combining the orthogonal test theory and the finite element simulation, the magnetic driving forcehas been calculatedforthe parameters of the electromagnetic coil and permanent magnet in different combinations of the values. The structure parameters of the electromagnetic coil and the permanent magnethave been optimizedto achieve the maximum magnetic driving force within the limited space.Themagnetic field distribution of the magnetic driving mechanismis simulatedby the optimized parameters. The simulation results show thatthe optimized magnetic driving force can satisfy the requirement of the medicine delivery, which provides a theoretical basis for developing the magnetic driving mechanism.

Key words: site-specific drug delivery, drug release driver, repeatedly release, orthogonal test, finite element simulation, magnetic field distribution

中图分类号:

鲁正平, 郭旭东, 许堂成, 秦锐华. 电磁-永磁式遥控施药胶囊驱动装置优化设计[J]. 系统仿真学报, 2018, 30(2): 747-752.

Lu Zhengping, GuoXudong, Xu Tangcheng, Qin Ruihua. Optimum Design of Remote Delivery Capsule’s Driving Mechanism Based on Electromagnetic-Permanent Magnet[J]. Journal of System Simulation, 2018, 30(2): 747-752.

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电磁-永磁式遥控施药胶囊驱动装置优化设计

Optimum Design of Remote Delivery Capsule’s Driving Mechanism Based on Electromagnetic-Permanent Magnet

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