Dynamics of Microbubble Confined in Concave Wall in Ultrasound Filed

doi:10.16182/j.issn1004731x.joss.201803014

Abstract

Abstract: The interactions between an ultrasound contrast agent (UCA) microbubble and a concave surface can be applied to understanding of the response of the UCA near blood vessel wall in ultrasound field. A dynamics model of microbubble near a concave wall is presented by a virtual image method and the acoustic reflection effects of the surface. The dynamic behavior of the microbubble is analyzed by numerical calculation. The results show that the microbubble vibration is suppressed near the wall. Inhibitory effects to microbubble vibration near rigid wall are stronger than that of near elastic wall. The microbubble vibration is easier to be suppressed with smaller concave radius or central angle of the concave wall. In the fully enclosed sphere, the larger the sphere radius is, the weaker the effect on the microbubble vibration becomes. This simulation model may provide reference for understanding the dynamics response of microbubble in vessel, and its application in ultrasound contrast imaging and drug delivery.

Key words: UCA microbubble, ultrasound, concave wall, dynamic response

CLC Number:

Hu Jiwen, Sun Jiana. Dynamics of Microbubble Confined in Concave Wall in Ultrasound Filed[J]. Journal of System Simulation, 2018, 30(3): 880-885.

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